Semilobar Holoprosencephaly With Single Umbilical Artery

Semilobar Holoprosencephaly with Congenital Oropharyngeal Stenosis in a Term Neonate

Background Holoprosencephaly (HPE) is often accompanied by a deficit in midline facial development; however, congenital oropharyngeal stenosis in neonates with HPE has not been reported before. We describe a case of a neonate with prenatally diagnosed semilobar HPE accompanied by congenital oropharyngeal stenosis. Case Report The patient was born at 39 weeks of gestation and developed dyspnea s...

Semilobar holoprosencephaly seen with diffusion tensor imaging and fiber tracking.

A neonate with semilobar holoprosencephaly was studied with diffusion tensor imaging and fiber tracking. Fiber tracking showed that the frontooccipital fasciculi were in continuity across the ventral midline, interposed between fused caudate and dysplastic fornices. Tractography of the posterior limbs of the internal capsules showed fibers arching ventrally toward the expected location of the m...

MR angiography of a 1-year-old girl with semilobar holoprosencephaly.

Holoprosencephaly Holoprosencephaly encompasses a variety of brain malformations and is thought to be a result of failure of cleavage of the prosencephalon into the diencephalon and telencephalon and/or stemming from a defect in the normal induction and patterning of the rostral neural tube, which normally occurs in the first 4 weeks after conception. We present a case of semilobar holoprosence...

A preterm infant with semilobar holoprosencephaly and hydrocephalus: a case report

INTRODUCTION Holoprosencephaly (HPE) is a rare presentation in newborns. It refers to an incomplete or absent division of the prosencephalon or forebrain into distinct cerebral hemispheres. CASE PRESENTATION A preterm baby girl, first of dizygotic twins, born at 26 weeks of gestation to a 45 year old mother, was prenatally diagnosed with ventriculomegaly on fetal ultrasonogram. At birth the b...

Early prenatal diagnosis of semilobar holoprosencephaly combined with a dorsal cyst and no facial defect.